Understand Your Fertility Condition

Explore medically reviewed guides to 19 common fertility conditions, from PCOS and endometriosis to unexplained infertility. Each guide explains causes, diagnosis, how the condition affects fertility, and which treatments are most effective.

19
Condition Guides
REI
Specialist Reviewed
2026
Last Updated
Author REI Specialist

MD, DGO Reproductive Medicine · Medically reviewed by

conditions-overview-hero.png

Did You Know: Up to 40% of infertility cases in India involve a diagnosable female fertility condition. Early diagnosis and targeted treatment significantly improve outcomes across all age groups.

REI Specialist Reviewed
PubMed & ICMR Sources
Updated Q1 2026
11 Comprehensive Guides
What You'll Find Here

About This Conditions Library

Fertility conditions range from hormonal imbalances like PCOS to structural issues like fibroids and tubal blockages. Understanding your specific condition — its causes, how it's diagnosed, and which treatments are best suited — is the foundation of an informed fertility journey.

Each guide in this library is written by medical writers with REI specialist oversight, citing peer-reviewed research from PubMed, ESHRE, and ICMR. Guides are updated quarterly and include practical next steps linking to relevant treatments, tools, and Q&A content.

Educational Purpose

These guides are for informational purposes only. A diagnosis must come from a qualified reproductive endocrinologist after clinical evaluation, blood tests, and imaging.

19 condition guides found

Age-Related

Age & Fertility

Natural decline in egg quality and quantity with age, with significant acceleration after 35. The most important single factor in fertility outcomes.

IVFEgg FreezingDonor Eggs
Read Guide
Hormonal

Hyperprolactinemia

Elevated prolactin levels that suppress ovulation and disrupt the menstrual cycle. One of the most treatable causes of infertility with medication.

MedicationSurgery
Read Guide
Structural

Hydrosalpinx

Fluid-filled, blocked fallopian tube that can significantly reduce IVF success rates if untreated. Treatment before IVF improves outcomes.

SurgerySalpingectomyIVF
Read Guide
Structural

Asherman's Syndrome

Intrauterine adhesions (scar tissue) that form inside the uterus after surgery or infection, reducing the uterine cavity and impairing fertility.

HysteroscopySurgeryIVF
Read Guide
Structural

Endometrial Polyps

Benign growths on the uterine lining that can interfere with embryo implantation. Found in up to 32% of women with unexplained infertility.

HysteroscopyPolypectomy
Read Guide
Male Factor

Varicocele

Enlarged veins in the scrotum that raise testicular temperature, damaging sperm production. The most common treatable cause of male infertility.

SurgeryEmbolizationIVF/ICSI
Read Guide
Male Factor

Azoospermia

Complete absence of sperm in the ejaculate. Affects 1% of men and 10-15% of infertile men. Treatment depends on whether the cause is obstructive or non-obstructive.

Micro-TESEICSISurgeryDonor Sperm
Read Guide
Structural

Adenomyosis

Endometrial tissue grows into the muscular wall of the uterus, causing heavy periods, pain, and impaired implantation.

IVFMedicationSurgery
Read Guide
Structural

Uterine Anomalies

Congenital uterine abnormalities such as septate, bicornuate, or arcuate uterus can affect implantation and increase miscarriage risk. Often correctable with hysteroscopic surgery.

SurgeryIVF
Read Guide
Age-Related

Premature Ovarian Insufficiency

Ovarian function declines before age 40. Rare but significant — affects 1% of women. Donor egg IVF offers the highest success rates for women with POI seeking pregnancy.

Donor Egg IVFHRT
Read Guide
Structural

Recurrent Pregnancy Loss

Defined as 2 or more consecutive pregnancy losses. Chromosomal abnormalities are the most common cause. PGT-A testing during IVF can significantly improve outcomes.

IVF + PGT-ATesting
Read Guide
Hormonal

Thyroid Disorders

Hypothyroidism and hyperthyroidism can disrupt ovulation, implantation, and early pregnancy. TSH screening is a standard part of the fertility workup in India.

MedicationIVF
Read Guide
Unexplained

Unexplained Infertility

No identifiable cause found after a full fertility workup. Affects 15–25% of couples. Empirical treatment with IUI or IVF is typically recommended after 12–18 months of trying.

IUIIVF
Read Guide
Structural

Blocked Fallopian Tubes

Tubal blockages prevent sperm and egg from meeting. Often caused by pelvic infections or endometriosis. IVF is the primary treatment, bypassing the tubes entirely.

IVFSurgery
Read Guide
Male Factor

Male Factor Infertility

Low sperm count, poor motility, or abnormal morphology contributes to 40–50% of infertility cases in India. Semen analysis is the first diagnostic step.

ICSIIVFIUI
Read Guide
Structural

Uterine Fibroids

Non-cancerous growths in the uterus that can interfere with implantation depending on size and location. Submucosal fibroids have the greatest impact on fertility outcomes.

MyomectomyIVF
Read Guide
Age-Related

Diminished Ovarian Reserve

Low AMH or antral follicle count indicating reduced egg quantity. Can occur at any age. IVF with tailored stimulation protocols remains the most effective treatment path.

IVFDonor Egg
Read Guide
Structural

Endometriosis

Endometrial-like tissue grows outside the uterus, causing pain and affecting egg quality and tubal function. Affects 1 in 10 women of reproductive age in India.

IVFSurgery
Read Guide
Hormonal

PCOS

The most common hormonal disorder affecting fertility. Irregular cycles, excess androgens, and polycystic ovaries. Highly treatable with lifestyle changes and targeted medication.

IVFIUIMedication
Read Guide
Next Step

Compare Treatments for Your Condition

Once you understand your condition, the next step is learning which treatments are most effective. Our treatment guides explain IVF, IUI, ICSI, egg freezing, and more — including success rates specific to each condition.

IVF Full guide
ICSI Coming soon
IUI Coming soon
Egg Freezing Coming soon

Check Your IVF Success Odds

Use our IVF Success Calculator to estimate your probability based on age, AMH, diagnosis, and prior cycle history.

Calculator coming soon

Ask a Fertility Specialist

Browse our curated Q&A library with answers from REI specialists on conditions, treatments, costs, and more.

Browse Q&A

Understand IVF Costs

Get a clear breakdown of treatment costs by city, clinic tier, and add-ons. Know what to budget before starting your journey.

View Cost Guide
Expert Answers

Common Questions About Fertility Conditions

Browse All Q&A

"Can I get pregnant naturally if I have PCOS?"

Yes — many women with PCOS conceive naturally, especially with lifestyle modifications and weight management. Ovulation induction medications like letrozole or clomiphene are often the first treatment step before considering IUI or IVF.

"Does endometriosis always require surgery before IVF?"

Not always. For mild to moderate endometriosis, IVF can be attempted directly. Surgery is typically recommended for endometriomas larger than 4cm or when endometriosis severely impacts ovarian access. The decision depends on ovarian reserve, age, and symptom severity.

"My husband has low sperm count — do we need IVF?"

It depends on the severity. Mild to moderate male factor infertility may be addressed with IUI. Severe male factor — very low count, poor motility, or zero sperm (azoospermia) — typically requires IVF with ICSI. A semen analysis and andrologist consultation will determine the right path.

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